Preheat oven to 400°F (200°C). Pierce 1 large or 2 medium sweet potatoes with a fork, place on the oven rack, and roast for 45–60 minutes until very soft. Let cool, scoop out the flesh, mash until smooth, and measure out 1 cup (240g).
Reduce oven temperature to 350°F (175°C). Grease a 9x5-inch loaf pan, line with parchment paper leaving an overhang on the long sides, then dust lightly with flour and set aside.
In a large bowl, whisk together the flour, baking powder, baking soda, cinnamon, and salt for 30 seconds until evenly combined. Set aside.
In a second large bowl, whisk together the mashed sweet potato and miso paste until smooth, then whisk in the oil, maple syrup, eggs (one at a time), milk, and vanilla until the mixture is glossy and completely homogeneous.
Pour the wet ingredients into the dry ingredients and fold gently with a spatula just until no large pockets of flour remain — do not overmix; a few small lumps are fine.
Toss the mixed seeds with ½ tsp olive oil; reserve 2 tablespoons for topping, then fold the rest into the batter. Pour batter into the prepared pan, smooth the top, and sprinkle with reserved seeds, pressing them lightly to adhere.
Bake at 350°F (175°C) for 55–60 minutes, without opening the oven for the first 50 minutes, until the top is golden brown and a toothpick inserted into the center comes out clean or with just a few moist crumbs (internal temp 200–205°F/93–96°C). Tent with foil if browning too quickly.
Cool the bread in the pan on a rack for 15 minutes, then lift out using the parchment overhang and cool completely on the rack for at least 45 minutes before slicing with a serrated knife.