If using fresh dragon fruit, scoop out the flesh and freeze for 2-3 hours until solid. If using frozen pitaya cubes or a puree packet, remove from freezer and let sit for 1-2 minutes to slightly thaw.
Pour 3/4 cup of coconut milk or almond milk into the blender first to create a vortex that pulls the frozen ingredients toward the blades.
Add the frozen dragon fruit, frozen banana slices, frozen mango chunks, and frozen pineapple chunks to the blender in that order.
Add chia seeds (if using), fresh lime juice, and honey or agave syrup (if desired) to the blender.
Secure the lid tightly and blend on low speed, gradually increasing to high. Blend for 45-60 seconds until completely smooth and creamy.
Stop the blender, scrape down the sides with a spatula, and blend for another 15-20 seconds until the texture is fully uniform. Add more liquid if too thick, or more frozen fruit if too thin.
Taste the smoothie and adjust sweetness or acidity with additional honey or lime juice if needed. Pour into serving glasses immediately.
Top with fresh dragon fruit slices, chia seeds, sliced kiwi, coconut flakes, or granola for added texture and visual appeal. Serve right away.