Remove cream cheese, sour cream, and eggs from refrigerator at least 1 hour before beginning. Preheat oven to 325°F (163°C). Lightly grease the 9-inch springform pan and wrap outside tightly with two layers of heavy-duty aluminum foil.
Pulse graham crackers in food processor until you have 2 cups (200g) of fine crumbs. Mix with 3 tablespoons (38g) sugar and 6 tablespoons (85g) melted butter until texture resembles wet sand. Press firmly into bottom and 1 inch up sides of prepared pan. Bake for 10 minutes until lightly golden.
In medium saucepan over medium heat, cook 1 cup (145g) blueberries and 3 tablespoons (38g) sugar for 3-4 minutes until berries burst. Whisk cornstarch with cold water, then add slurry and lemon juice to saucepan. Cook 1-2 minutes until thickened. Stir in remaining 1 cup (145g) blueberries, remove from heat, and cool to room temperature.
In stand mixer with paddle, beat 24 oz (680g) softened cream cheese on medium speed for 3 minutes until smooth. Add 1 cup (200g) sugar and beat 2 more minutes until fluffy and pale. Add sour cream, lemon zest, and vanilla; mix on low until just combined.
Add eggs one at a time, mixing on low just until yellow disappears. Stop immediately after last egg is incorporated to avoid overmixing. Scrape bowl and fold gently with spatula to ensure even combination.
Pour filling over pre-baked crust and smooth top with offset spatula. Tap pan on counter 2-3 times to release air bubbles.
Place foil-wrapped pan in roasting pan and pour hot water into roasting pan until 1 inch up sides of springform pan. Bake at 325°F (163°C) for 55-65 minutes. Cheesecake is done when edges are set and center 2-3 inches has a gentle wobble like Jell-O.
Turn off oven without opening door and let cheesecake rest for 1 hour. Then crack oven door open and cool for 30 more minutes. Remove from roasting pan, peel away foil, and run thin spatula around edge to loosen. Cool on wire rack to room temperature (1-2 hours).
Cover cheesecake loosely and refrigerate at least 8 hours or overnight to fully set. When ready to serve, remove springform ring and spoon chilled blueberry topping over cheesecake or individual slices.